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Purpose. This study examines the influence of football match outcomes on the emotional states, work capacity, and motivation of children across different age groups, particularly in the context of Georgia's historic qualification for the European Championship in 2024. Recognizing the multifaceted impact of sports on mood and cognition, we explore how the euphoria resulting from a win can vary significantly based on age.
Methods. A survey involving 40 school-aged children (11-17 years old) was conducted a week after Georgia’s victory against Greece, measuring emotional responses and their subsequent effects on work performance and motivation.

Results. Children aged 11 to 13 experienced the highest levels of euphoria, rating their happiness at 5 out of 5, while those aged 14 to 16 reported a score of 4.5 and 17 to 18-year-olds scored 4.7. In terms of work capacity, the average score was 3.1, with the 17-18 age group showing the highest rating at 3.71 and the 14-16 group the lowest at 2.68. Motivation levels averaged 4.1, peaking at 4.4 among 17-18-year-olds, whereas the 14-16-year-olds displayed no significant increase.
Conclusion. The findings reveal that younger children are more emotionally responsive to victories, while older adolescents demonstrate greater resilience and utilize positive emotions to enhance their focus and motivation. This underscores the importance of understanding emotional dynamics in sports, providing insights into how to foster resilience, emotional intelligence, and community among young fans and players. By cultivating these qualities, we can support the holistic development of youth, ultimately contributing to their growth as individuals both on and off the field.

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Cardiovascular diseases (CVD) remain the leading cause of mortality in both industrialized and developing countries, including Russia. Recent evidence suggests that atherosclerosis, a major precursor to CVD, begins in childhood and adolescence and progresses throughout life due to genetic and modifiable risk factors. This study focuses on new screening methods for early diagnosis of cardiovascular pathology.

Purpose. To assess the functional state of the cardiovascular system and adaptive reserves of children and adolescents in the Orenburg region.
Methods. The study included 518 children aged 6 to 18 years from urban and rural areas in Orenburg and the Orenburg region. The adaptive capacity and stress levels of their regulatory systems were measured using the "Varikard-Express" software complex (Russia). Additionally, the functional state of the cardiovascular system was evaluated through the "Cardiovisor-06s" computer heart screening system (Russia), which provides 3D heart visualizations ("heart portraits").
Results. Findings revealed significant adaptation disorders, including pronounced stress and disruption of the adaptation process, which were more prevalent among urban residents compared to rural residents (60.57% vs. 39.42%). Age-based analysis indicated that children aged 10-14 exhibited the highest rates of adaptation disorders, with 52.34% experiencing pronounced or sharply pronounced stress of the regulatory system compared to other age groups (p < 0.05).
Conclusion. The study identified prevalent deviations in cardiovascular function and adaptive capacity among children and adolescents. More than half of the participants demonstrated varying levels of cardiovascular dysfunction, and over one-third had disruptions in adaptive processes. These findings underscore the importance of early screening for cardiovascular and adaptation-related issues in youth to facilitate timely interventions.

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This article is dedicated to Izgali Bainashev, one of the founders and key organizers of the Department of Inorganic Chemistry at Marat Ospanov West Kazakhstan Medical University.

Bainashev, a distinguished figure in the field of chemistry, was among those repressed during the Soviet era.
Despite his brief tenure as the head of the department at Aktobe State Medical Institute, he succeeded in establishing a well-organized department with a highly qualified team, ensuring a robust educational process.
The memory of such influential figures is honored with deep respect.

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This study aims to analyze the results of a comprehensive examination of children with congenital anomalies of the internal auditory canal (IAC) and propose an X-ray-based classification of these pathologies, drawn from our clinical experience.

Methods. We analyzed a group of 250 children (500 ears) examined between 2012 and 2024. These children presented with varying degrees of bilateral or unilateral sensorineural, conductive, or mixed hearing loss of unknown etiology. Following audiological examinations, high-resolution computed tomography (CT) of the temporal bones was performed. IAC assessment followed a structured algorithm, evaluating the presence, diameter, shape, state of the IAC floor, and cochlear field, as well as its position relative to surrounding structures. Patients with identified IAC congenital anomalies were referred for 3T magnetic resonance imaging (MRI) of the brain, specifically targeting the auditory nerves.
Results. Congenital anomalies of the IAC were identified in 63 patients (25.2%), including stenosis, duplication, bulbous expansion, and partial or complete obliteration of the cochlear field. Audiological assessments in these patients indicated that a bone-air-bone gap may be present in some cases of congenital IAC anomalies, and otoacoustic emissions were recorded in others. Based on these findings, a classification system for IAC anomalies was proposed.
Conclusion. Congenital anomalies of the IAC represent a significant cause of hearing loss, necessitating specific patient management strategies. Audiological characteristics alone are insufficient to localize these anomalies, emphasizing the importance of high-resolution temporal bone CT and, where appropriate, 3T MRI in diagnosing and managing these cases. Early detection of IAC anomalies allows for more targeted rehabilitation and treatment plans for children with congenital hearing loss.

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Gastric cancer remains a leading cause of cancer incidence worldwide. An essential aspect of comprehensive strategies to reduce the incidence of malignant neoplasms is the development of effective early diagnostic methods.

Purpose. This study explores the relationship between the expression of the cell proliferation marker Ki-67 and various factors, including age, gender, disease stage, and tumor differentiation, utilizing immunohistochemical analysis
Methods. This comparative descriptive study involved surgical specimens from 109 patients with gastric cancer stages 0-IIIC, collected during operations at the pathology department of Marat Ospanov Medical Center between 2021 and 2022. Histological and immunohistochemical evaluations were conducted in the morphological laboratory of the Department of Histology at WKMU. The data obtained were subjected to statistical analysis.
Results. Our findings revealed a significant correlation between Ki-67 expression levels and the histopathological grade of gastric cancer (p=0.039). However, no statistically significant relationships were observed between Ki-67 expression and other factors such as pTNM stage (p=0.894), age (p=0.664), gender (F=1, M=2; p=0.928), or tumor localization (cardiac=1, body=2, antral and pyloric=3; p=0.860).
Conclusion. The significant relationship between Ki-67 expression and histopathological grade (p=0.039) suggests its potential utility in identifying patients with aggressive tumors who may benefit from adjuvant therapy.

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This study evaluates the impact and effectiveness of advanced practice nurses (APNs) at City Polyclinic No. 6 in Almaty, focusing on improving the quality of medical services. The research involved a patient satisfaction survey to assess the quality of care provided by APNs operating independently.
Purpose. To comprehensively assess the effectiveness of advanced practice nurses at the Family Health Center in improving patient care.

Methods. The study utilized a combination of statistical data analysis from City Polyclinic No. 6 for 2024 and a socio-hygienic analysis. Data were collected for two periods: from October 1, 2023, to December 1, 2023, and from January 1, 2024, to March 1, 2024.
Results. The statistical analysis revealed a significant increase in the number of patients receiving care from the four advanced practice nurses. The number of independent consultations provided by these nurses tripled, rising from 43% in October 2023 to 67% in March 2024 (p < 0.05). Additionally, a patient satisfaction survey showed that 94% of respondents were satisfied with the services provided by the APNs. However, 71.67% attributed dissatisfaction to technical issues (such as the Damumed program), while 23.33% cited a high patient load as a challenge.
Conclusion. This study highlights the significant positive impact of advanced practice nurses on patient satisfaction and healthcare quality, particularly in independent practice settings. These findings are increasingly relevant given the current strain on doctors in polyclinics.

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The COVID-19 pandemic has led to hundreds of millions of infections and six million deaths globally, presenting the medical community with the challenge of addressing long COVID, or post-COVID syndrome, characterized by persistent symptoms following the acute phase of SARS-CoV-2 infection. Studies indicate that, similar to other viral infections, a variety of systemic and specific conditions can continue or re-emerge in individuals recovering from COVID-19. This phenomenon has garnered significant attention from researchers worldwide and has emerged as a pressing social issue.

Purpose. This review examines the prevalence of post-COVID conditions, their clinical manifestations, and their association with COVID-19 vaccinations.
Methods. We conducted a literature search in the Scopus and PubMed databases for articles published between 2021 and 2023, using keywords such as "post-COVID syndrome," "vaccination against COVID-19," "post-COVID condition," and "long COVID." A total of 100 publications were analyzed, with 92 articles meeting the study criteria. We focused on literature addressing post-COVID-19 conditions globally and vaccine prevention strategies, revealing a direct link between vaccination and a reduced risk of developing post-COVID symptoms, as well as in patients with existing post-COVID syndrome.
Conclusion. As widespread vaccination efforts continue and new variants of SARS-CoV-2 emerge that tend to cause less severe disease, it appears that the frequency and severity of post-COVID syndrome may be decreasing. Nonetheless, further investigation is essential. Providing updated data is crucial for informing organizations and allocating resources effectively to mitigate the social, economic, and public health impacts of these conditions.
Keywords. Post-COVID syndrome, vaccination against COVID-19, post-COVID condition, long COVID