Annotation

Antibiotic resistance poses a serious threat to global health, fueled by the widespread and often uncontrolled use of antibiotics in both medicine and agriculture. Factors such as inappropriate prescribing, poor compliance with sanitary standards in healthcare settings, and environmental

pollution contribute to the emergence and spread of resistant bacterial strains.
Developing new antibiotics is increasingly challenging due to the rapid evolution of resistance and limited discovery of novel compounds. Traditional approaches have largely been exhausted, and although modern technologies such as systems biology and discovery platforms offer potential, they have yet to produce significant breakthroughs.
Artificial intelligence (AI) is emerging as a transformative tool in the development of antibacterial agents. Deep learning algorithms can analyze chemical structures and predict biological activity, as seen in the discovery of halicin, a compound with a novel mechanism that prevents resistance development. AI also facilitates the optimization of treatment regimens through personalized therapy, minimizing side effects.
Additionally, virtual screening expedites drug discovery, reduces costs, and enhances efficiency. Future directions involve improving the transparency and interpretability of AI models to ensure safer clinical applications.

Annotation

This article explores the relevance of stroke rehabilitation research across various countries, highlighting it as a pressing issue in global healthcare. The review focuses on the prevalence of stroke worldwide and the diverse approaches employed to enhance the quality of medical rehabilitation.

It examines historical perspectives, definitions, and core principles of rehabilitation, as well as its influence on the health outcomes and quality of life of stroke patients. The analysis identifies innovations and best practices implemented in different healthcare systems, allowing for a comparative assessment of rehabilitation models. By studying international experiences, the review reveals variations in the structure and delivery of rehabilitation services and provides insights into how different countries address the long-term needs of stroke survivors. As global health systems seek to improve rehabilitation outcomes, understanding these international approaches is increasingly essential.

Annotation

Meteorological changes contribute to the spread of magnetic waves, which can have adverse effects on human health. According to meteorological and scientific research, the lower atmospheric layers contain small solid particles, referred to as magnetic dust, that may influence

electromagnetic activity. These electromagnetic waves are capable of inducing irreversible pathological changes in the internal environment of the human body.
Recent atmospheric shifts have resulted in abnormal fluctuations in air temperature, pressure, and density. These phenomena are exacerbated by the persistent presence of internet-generated waves, which would typically dissipate in the upper atmospheric layers. Increases in airborne gases and intensified magnetic fluctuations are additional factors contributing to negative health outcomes. This study provides a medical assessment of the effects of these meteorological and environmental changes, highlighting the need for ongoing monitoring and preventive measures.

Annotation

Current forensic medical literature offers limited methodologies for determining the age of bone fractures, primarily focusing on ribs and the presence of fractographic signs along fracture edges. However, there is a notable absence of established diagnostic criteria for assessing the age

of skull fractures, especially in cases complicated by purulent infection. This article presents a forensic case study involving a skull fracture with delayed healing due to secondary purulent infection. In such instances, existing approaches provide only approximate estimations of the time of injury. Based on the findings, we propose that accurate age determination of skull fractures should rely on a detailed analysis of the morphological characteristics of the fracture edges, alongside a comprehensive evaluation of all associated injuries and their traces identified during both external and internal examinations.

Annotation

In the modern world, digital technologies have permeated all areas of life, significantly influencing professional activities and reshaping the skillsets required for career success. This shift necessitates the adaptation and development of additional competencies, especially in the medical field

This study explores the application of the case method in the digital age as a pedagogical tool for training medical students to meet contemporary challenges while maintaining psychological well-being. It examines current trends and challenges posed by digitalization and highlights the competencies needed by future medical professionals.
The case method has proven effective in fostering critical thinking, analytical reasoning, leadership, and social communication skills. The study outlines specific strategies and practices that enhance the effectiveness of this method in the educational process, underscoring its potential to support students’ personal growth and well-being in the context of digital transformation.
Practical recommendations are offered on how to develop and implement case-based learning, including guidance on case design, instructional organization, and assessment of learning outcomes. The findings confirm that integrating digital tools with the case method can significantly strengthen the professional readiness and resilience of medical students.

Annotation

This study aims to preserve the historical memory of the contribution made by veterans of the Great Patriotic War to the establishment and development of the Department of Medical and Biological Chemistry at the Marat Ospanov West Kazakhstan Medical University. It highlights their

pivotal role in laying the foundations of scientific traditions, building a pedagogical school, and advancing the system of higher medical education in the region. Their legacy continues to shape academic and research excellence at the university.

Annotation

This article provides an in-depth overview of the life and legacy of M. Ospanov, as a scholar, politician, and public figure. It presents a comprehensive analysis of his scientific, pedagogical, and political contributions, emphasizing his pivotal role in shaping Kazakhstan’s political

and economic landscape during its early years of independence. Drawing on historical documents, memoirs, and scientific literature, the study offers a well-rounded portrait of Ospanov’s career and personal values. He occupies a unique position among Kazakhstan’s state and public leaders, particularly as the first Chairman of the Mazhilis of the Parliament of the Republic of Kazakhstan, where he played a central role in establishing the legislative framework of the country. Beyond his political impact, he was also a respected economist, educator, and scientist who worked for many years at the Aktobe Medical Institute. Ospanov’s initiatives and reforms, launched during Kazakhstan’s transitional period, significantly contributed to the country’s socio-economic stability. His works on public administration, tax policy, budgetary structure, and the foundations of parliamentarism remain relevant to this day. The article aims to introduce younger generations to his legacy, moral values, and life journey as a model of civic engagement and leadership.